7. Parkinson’s Medications
Certain anticholinergics like trihexyphenidyl raise flags.
6. Zolpidem (Ambien)
Popular sleep aid; studies suggest higher use correlates with risk.
But the next are everyday staples…
5. Lorazepam or Diazepam
Benzodiazepines for anxiety; long-term use associated in some cohorts.
4. Amitriptyline
Tricyclic for pain or depression; strong anticholinergic effects.
3. Oxybutynin
Common bladder drug; high cumulative risk noted.
Hold on—these top the lists…
2. Tolterodine or Similar
Overactive bladder meds; persistent exposure concerns.
1. Diphenhydramine (Benadryl)
OTC allergy/sleep aid; most studied for dementia association.
- Review meds annually
- Consider alternatives
- Lowest dose shortest time
ADVERTISEMENT
